Jobs: Technical Assistant (d/f/m)

Beschreibung

Company description

The mission of the Berlin Institute of Health at Charité (BIH) is medical translation: transferring biomedical research findings into novel approaches to personalized prediction, prevention, diagnostics and therapies and, conversely, using clinical observations to develop new research ideas. The aim is to deliver relevant medical benefits to patients and the population at large. Since 2021 the BIH has been integrated into Charité as its so-called third pillar.

For the team of Prof. L. Vallier starting from now until September, 25th 2028 we are looking for a Technical Assistant (d/f/m) in full-time (38,5h/week).

The Vallier lab based at the BCRT will takes advantage of human induced pluripotent stem cells and primary organoids to understand liver development in human and to generate cells with a clinical interest for modelling diseases and for cell-based therapies applications. More precisely, we investigate the molecular mechanisms controlling cell fate decisions during human development and exploit the resulting knowledge to produce liver cells especially hepatocytes and chol-angiocytes.

What you can expect

The candidate will join the ARPA-H project LIVE which aims to bioprint an entire human liver for transplantation in the context of acute liver disease. The role of the candidate will be (i) to identify and to characterise GMP grade human induced Pluripotent Stem Cell line suitable for the project, (ii) to produce, to charactersie and to quality control liver cells at large quantity for the project. For that, they will develop new methods for to differentiation hiPSC lines using bioreactor. The resulting cell will be then used to bioprint artificial liver in vitro in collaboration without the international network of collaborators of the ARPA-H LIVE program.

Cell culture production (grow, characterise, differentiate human pluripotent stem cells)
Application of previously determined analytical procedures
Filling, operation and calibration/programming of the instruments to be used
Evaluation and interpretation of the analysis results with regard to plausibility and quality
Receipt, documentation and tracking of valuable samples
Review and qualitative evaluation of the sample
Technical elaboration of the experimental setup
Maintenance of laboratory equipment, if necessary organization of external service and repair measures.
Supervision of general laboratory operations and organization
Maintenance of the laboratory workplace, taking into account occupational health and safety and disposal guidelines
Ordering and stocking, e.g. of consumables, media and solutions
Performance of analytical procedures (application of previously determined analytical procedures,filling, operation and calibration/programming of the instruments to be used, evaluation and interpretation of the analysis results with regard to plausibility and quality)

What you bring along

Bachelor or equivalent in cell biology, bioengineering or regenerative medicine.
Experience in tissue culture especially with human Pluripotent Stem Cells.
Basic experience in flow cytometry, QPCR, and confocal imaging.
Experience in working independently while keeping a strong team spirit.
Strong self-motivation, organizational skills, and ability to lead and develop scientific projects.
Scientific curiosity, analytical thinking, and interest in contributing to projects.
Ability to work in a team of young scientists, to be flexible, and flourish in a fast-paced environment.
Strong communication and interpersonal skills, ability to work collaborate effectively with individuals of different backgrounds in a multidisciplinary team, team orientated with excellent organizational skills including project management and good record keeping important.
Fluent English

What we offer you

A varied job in a forward-looking research institute
Pay group E9b TVöD VKA-K. The classification is based on qualifications, the respective experience level is calculated on the basis of professional experience. The annual salary (gross) is stated for a full-time position without special or additional payments. The collective agreement can be found here.
Additional benefits customary in the public sector (including annual special payment, company pension scheme (VBL), capital-forming benefits)
Flexible working
30 vacation
Various support offers
Very good
Mobile citizens‚ office on site
Corporate benefits (travel, leisure, shopping, etc.), Charité Gympass, JobRad
Very easily accessible and attractive workplace at the Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin

We live diversity!

We welcome applications from people with diverse backgrounds, regardless of gender, nationality, ethnic and social origin, religion and ideology, disability, age, sexual orientation and identity. Applications from women are expressly encouraged. Severely disabled and equivalent applicants will be given special consideration if they have the same qualifications and suitability.

We believe that diverse teams representing a wide range of experiences, perspectives and backgrounds enrich our research and work.

Please submit your application via our online application form with a letter of motivation, curriculum vitae (without photo, without age statement and without information about your marital status) and other relevant attachments (such as employer references, degree certificates, etc.).

Note: If you have a foreign degree, please submit proof of recognition of your degree in Germany with your application. The proof can be obtained via the anabin database. Please note that it may be necessary to obtain a certificate assessment from the ZAB. You can find more information here.

Proof of measles immunity / measles vaccination is a prerequisite for employment for those born after 1970.

You can find more information about BIH here.

Application

Everyone is welcome at the Charité, regardless of age, religion, gender, gender identity, sexual orientation, nationality, disability, ethnic or social background. We are committed to equal opportunities and inclusion.